I imagine some things remain the same as what we got originally in 2099. In Tom D's last regular story for ASM in the 90s prior to the Mackie/Byrne relaunch, Miguel and Mayday can be seen among several Spider-Heroes being discussed by the historians in the future.
In the UK Spider-Man comics, they revealed that Peter's future included the MC2 status quo, and eventually we see the future of 2099 as we've always known it.
The original 2099? The 2009/2099 miniseries or the one in Secret Wars?