The whole concept of 'the box' is just too.. far fetched. It's so advanced ANCIENT Gods thought it was mystical? Huh? Wha? And they all just 'knew' about it back on E3 although it's so ancient.. and has been gone for so long? It's effects on others.. well, if that universe is so danged evil-ishes then how do they have (we are assuming from their prisoner) heroic figures there?
Also, with the seeming effects it has on others, what makes Constantine so immune.. being damaged goods? Seems it's make more sense if he was an E3 guy, himself.
As far as Atomica, her being able to fool the Justice League AND Waller when she's only been around for five years, that seems pretty daft. And Martian Manhunter?!?! There's just too many forced plot points here for it to make anyone satisfied.
Also, the grandiose flare in attaining the box with EVERYONE there.. battered yes, but a handful of villains are now basically staring down the barrell of an E-Prime shotgun with the Justice League, Justice League of America, and Justice League Dark all assembled beforee them. Was the plan to weaken them all and then finish theem? There's no communication between the two sides, you'd think they'd step through then freak out (all like Power Ring) when they saw the assembly before.
The only one missing right now is OMAC. I think the story should end with him showing up, no one has to explain how to counter the Pandora's Box silliness, and have him mop the floor with the Crime Syndicate, the other heroes tossing anyone back into the ring that tries to get away from him