I had fun reading it.
The main weakness of the story : In my opinion, this Marvel event is only a guilty pleasure for veteran readers because the pleasure comes from the discovery of the Easter eggs. To really understand the interactions of the characters, it requires a deep knowledge of the Marvel Universe (alternative timelines, clones, the history of Spider-Man, Captain Universe, Captain Britain Corps, 2099, SpOck, Gwen...)
I am not certain that it is possible to enjoy anything in the story without a previous knowledge of the characters (Morlun, Ezekiel, Kaine, Ben Reilly, May Parker, SpOck, ...) Thus, it is not an autonomous storyline.
So : fun but not extraordinary.
Like most Marvel events (Inferno, Acts of Vengeance, Age of Apocalypse, Civil War, Dark Age...).
I really don't believe comics should cater to new readers since all indications are that there are LESS people reading comics, not more. So it is pretty unlikely a relatively new comic reader is reading this. I think there's been enough info that it shouldn't be too confusing. Most of the alt Spider-Men are Peter's life exactly as it was except there was a point where it diverged, such as keeping the Galactic powers, keeping the six arms, etc... Only in a handful of cases is it a completely different unfamiliar reality and I guess the books have done a good job of explaining it.
I'd also argue some of the Edge of Spider-verse issues would be INCREDIBLY new reader friendly. You could make some serious comic fans if you handed an anime fan a copy of the Sp//dr issue.