The Howling Commandos scene really throws the rest of the issue off. What a missed opportunity too, since Hickman could have created new characters in a SHIELD team instead that could have fit into the timeline much batter.
I guess Fantomex aged to adulthood in 10 years, but they don't say how.
Not too keen on Weapon 10 being Fantomex's twin, but why not, I guess.
Weapon 13 (Fantomex) didn't come about until just several years ago Marvel time. It's already established that he was artificially aged rapidly. He was totally artificially created.